CRC 656 B07 - Mathematical Modelling of Atherosclerotic Plaque Formation Based on Data from Multiparametric Imaging
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/07/2013 - 30/06/2017 | 1st Funding period
Description
Most vascular pathologies arise from atherosclerosis. Atherogenesis is an inflammatory process mainly triggered by low-density lipoproteins entering the intimal layer of arteries. This phenomenon in turn is regionally related to a blood flow dependent change in endothelial shear stress. We aim at numerical modeling of atherogenesis based on multiparametric imaging data of vessel architecture, blood flow and vascular inflammation. Simulation-based characterisation of the dependence of plaque formation on critical parameters should finally support our understanding of plaque development.
Keywords: Mathematical Modelling; Atherosclerotic Plaque; Multiparametric Imaging
Website of the project: http://www.uni-muenster.de/Sfbmobil/en/projekte/methoden/b7.php
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Ohlberger, Mario | Professorship of Applied Mathematics, especially Numerics (Prof. Ohlberger) |
| Wierling, Stefan | Professorship of Applied Mathematics, especially Numerics (Prof. Ohlberger) |
Applicants from the University of Münster
| Ohlberger, Mario | Professorship of Applied Mathematics, especially Numerics (Prof. Ohlberger) |
Research associates from the University of Münster
| Meyer, Falk | Professorship of Applied Mathematics, especially Numerics (Prof. Ohlberger) |
| Wierling, Stefan | Professorship of Applied Mathematics, especially Numerics (Prof. Ohlberger) |