Negative Ion-Mode N-Glycan Mass Spectrometry Imaging by MALDI-2-TOF-MS

Soltwisch J.; Heijs B.

Research article (journal)

Abstract

Matrix-assisted laser desorption/ionization mass spectrometry imaging with laser-induced postionization (MALDI-2-MSI) has proven a powerful tool for the in situ analysis of N-linked glycosylation, or N-glycans, directly from clinical tissue samples. Here we describe a sample preparation protocol for the analysis of N-glycans from formalin-fixed, paraffin-embedded tissue sections.

Details zur Publikation

Publisher:
Release year: 2023
Publishing company: Humana Press Inc.
Language in which the publication is written: English
Link to the full text: https://api.elsevier.com/content/abstract/scopus_id/85164247241