Leifert, D.; Artiukhin, D. G.; Neugebauer, J.; Galstyan, A.; Strassert, C. A.; Studer, A.
Research article (journal)
Arylisonitriles (2 equivalents) react with alkyl and perfluoroalkyl radicals to form 2-alkylated indole-3-imines via two sequential additions to the isonitrile moiety followed by homolytic aromatic substitution. The three component reaction comprises three C–C bond formations. The endocyclic imine functionality in the products is more reactive in follow up chemistry and hydrolysis of the exocyclic imine leads to 3-oxindoles that show fluorescence properties.
Release year: 2016
Language in which the publication is written: English
Link to the full text: http://dx.doi.org/10.1039/C6CC02284G