Magnesium Shifts after Acute Exhaustive Exercise

Mooren FCh, Lechtermann A, Fromme A, Thorwesten L, Völker K

Abstract in digital collection (conference)

Abstract

Magnesium (Mg) is the second most abundant intracellular cation with modulating properties in a number of metabolic processes, e.g., in glycolysis, and intracellular signalling processes, e.g., regulationof ion channels and ion transporters. So far, there are conflieting data about the regulation of Mg during exercise. The present study investigated the changes of free and total Mg indifferent compartments after a stepwise running ergometer test. Free Mg was determined using fluorescense spectroscopy, and ionsensitive microelectrodes while total magnesium was investigated using atomic absorbance spectroscopy and photometry. At the end of the ergometer test free magnesium in whole blood and serum decreased to about 0.03 mmol/1 and 0.05 mmol/1,respectively, while total Mg was unchanged. On the other hand, the eoncentration of free Mg increased by about 0.1 mmol/1 in thrombocytes and erythrocytes. The present study demonstrates changes of extracellular and intracellular free magnesium concentration in opposite directions suggesting a shift of at least a quantum of extracellular Mg to the intracellular compartment. The magnitude of this shift should be high enough to influence intracellular signalling and meta bolic processes.

Details zur Publikation

Publisher: Halle M
Release year: 1999
Publishing company: Thieme
Language in which the publication is written: English
Event: Stuttgart