Palladium-Catalyzed Intermolecular Decarboxylative Coupling of 2-Phenylbenzoic Acids with Alkynes via C-H and C-C Bond Activation
Wang CY, Rakshit S, Glorius F
Research article (journal)Abstract
A novel protocol for palladium-catalyzed intermolecular formal [4 + 2] annulation of 2-phenylbenzoic acids with alkynes is described. Acridine is shown to be essential for the high reaction efficiency. Phenanthrene derivatives are formed in moderate to good yields without coupling (pseudo)halides or organometallic species.
Details about the publication
Journal: Journal of the American Chemical Society (J. Am. Chem. Soc.)
Volume: 132
Issue: 40
Page range: 14006-14008
Status: Published
Release year: 2010 (13/10/2010)
Language in which the publication is written: English
DOI: 10.1021/ja106130r
Keywords: aromatic carboxylate salts benzoic-acids direct arylation annulation olefination mechanism derivatives cleavage indoles arene
Authors from the University of Münster
| Glorius, Frank | Professur für Organische Chemie (Prof. Glorius) |
| Rakshit, Souvik | Organic Chemistry Institute |