Dynamic Peptides as Biomimetic Carbohydrate Receptors.

Rauschenberg M., Bomke S., Karst U., Ravoo B.J.

Research article (journal)

Abstract

Finding the needle in the haystack:A dynamic combinatorial library(DCL)of peptides was created using the disulfide-exchange reaction of cysteines. Three cyclic peptides were found to be selective receptors for carbohydrates in water. One ofthese, HisHis, formed preferentially in a DCL in the presence of the neurotrans- mitter NANA.

Details zur Publikation

Pages: 6
Release year: 2010
Language in which the publication is written: English