CRC 1459 B05 - Adaptive cell-matrix nanosystems

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration: 01/01/2021 - 31/12/2024 | 1st Funding period

Description

This interdisciplinary project aims at the generation of a biosynthetic material, in which mammalian cells are utilized as information-processing elements that sense, integrate, and feedback on physiological stimuli. Using the expertise of three laboratories specialized in cell biology/biophysics, biomaterial science, and coordination chemistry, 3D hydrogels harbouring mesenchymal stem cells and novel metal-organic based tension sensors, will be generated. The resulting hybrid nanosystem should sense and adapt to various stimuli including mechanical forces, biochemical signals, and light.

Keywords: nanoscience; adaptive soft materials