Protein-protein interaction (PPI) inhibitors of human HSP90 identified by flow cytometer based screening
Bopp B, Ciglia E, Gohlke H, Jose J
Abstract in digital collection (conference) | Peer reviewedAbstract
Computational characterization of hot spots within the dimerization interface of HSP90 were experimentally validated via Autodisplay and flow cytometric analysis. The results shown indicate, that this method can be used to identify new small molecules PPI inhibitors targeted towards the HSP90 dimerization interface.
Details about the publication
Status: Published
Release year: 2014
Language in which the publication is written: English
Conference: Forschung der Chemischen Institute (Symposium), Münster, undefined
Authors from the University of Münster
| Jose, Joachim | Professur für Pharmazeutische Chemie (Prof. Jose) Center of Interdisciplinary Sustainability Research (ZIN) |