Preparation of conjugated 1,3-enynes by Rh(III)-catalysed alkynylation of alkenes via C-H activation.
Collins KD, Lied F, Glorius F
Research article (journal) | Peer reviewedAbstract
An experimentally simple additive-free Rh(III)-catalysed direct alkynylation of alkenes has been developed. This protocol employs commercially available TIPS-EBX as the alkyne source, giving access to conjugated terminal enynes following a simple silyl-deprotection. This method has also been applied to arenes.
Details about the publication
Journal: Chemical communications (Chem. Commun.)
Volume: 50
Issue: 34
Page range: 4459-61
Status: Published
Release year: 2014 (04/05/2014)
Language in which the publication is written: English
DOI: 10.1039/c4cc01141d
Authors from the University of Münster
| Glorius, Frank | Professur für Organische Chemie (Prof. Glorius) |