Direct and efficient N-heterocyclic carbene-catalyzed hydroxymethylation of aldehydes.
Kuhl N, Glorius F
Research article (journal)Abstract
The N-heterocyclic carbene-catalyzed coupling of several aldehydes with paraformaldehyde is reported, directly providing the corresponding valuable hydroxymethyl ketones. Results of first mechanistic experiments for this remarkably selective transformation are also provided.
Details about the publication
Journal: Chemical communications (Chem. Commun.)
Volume: 47
Issue: 1
Page range: 573-575
Status: Published
Release year: 2011 (07/01/2011)
Language in which the publication is written: Uncoded languages
DOI: 10.1039/c0cc02416c
Authors from the University of Münster
| Glorius, Frank | Professur für Organische Chemie (Prof. Glorius) |
| Kuhl, Nadine | Organic Chemistry Institute |