Olefin-Oxazolines (OlefOx): Highly Modular, Easily Tunable Ligands for Asymmetric Catalysis
Hahn BT, Tewes F, Frohlich R, Glorius F
Research article (journal)Abstract
An efficient three-step synthesis allows the new highly modular family of olefin-oxazoline ligands (OlefOx; see picture) to be exploited in asymmetric catalysis. The ease of electronic and steric variation and the successful application in the highly enantioselective rhodium-catalyzed conjugate addition of aryl boronic acids to cylic enones demonstrate the importance of this new ligand class.
Details about the publication
Journal: Angewandte Chemie International Edition (Angew. Chem. Int. Ed.)
Volume: 49
Issue: 6
Page range: 1143-1146
Status: Published
Release year: 2010 (31/12/2010)
Language in which the publication is written: English
Keywords: homogeneous catalysis ligand design olefins oxazolines rhodium enantioselective diethylzinc addition efficient oxidative conversion chiral diene ligands allylic substitution 1,4-addition reactions organozinc reagents conjugate addition phosphite ligands steering ligands boronic acids
Authors from the University of Münster
| Glorius, Frank | Professur für Organische Chemie (Prof. Glorius) |