Efficient oxidative synthesis of 2-oxazolines

Schwekendiek K, Glorius F

Research article (journal)

Abstract

New methodology for the synthesis of variously substituted 2-oxazolines and one dihydrooxazine using aldehydes, amino alcohols, and N-bromosuccinimide as an oxidizing agent is described. This one-pot synthesis is characterized by mild reaction conditions, broad scope, high yields, and its preparative simplicity.

Details about the publication

JournalSynthesis
Issue18
Page range2996-3002
StatusPublished
Release year2006 (18/09/2006)
Language in which the publication is writtenEnglish
Keywordsamino alcohols oxidative coupling oxazolines oxazolidines N-bromosuccinimide phenolic schiffs bases diels-alder reactions one-pot synthesis asymmetric catalysis amino-alcohols practical synthesis chiral auxiliaries 2-arylbenzoxazoles oxazolines versatile

Authors from the University of Münster

Glorius, Frank
Professur für Organische Chemie (Prof. Glorius)