N-formylation of amines by methanol activation.

Ortega N, Richter C, Glorius F

Zusammenfassung

The homogeneous catalyzed dehydrogenation of methanol in a synthetically valuable cross-coupling reaction was achieved. By the use of a simple ruthenium-N-heterocyclic carbene complex, MeOH and primary or secondary amines can be converted into formamides.