The CH Activation/1,3-Diyne Strategy: Highly Selective Direct Synthesis of Diverse Bisheterocycles by Rh(III) Catalysis.

Yu DG, de Azambuja F, Gensch T, Daniliuc CG, Glorius F

Sonstige wissenschaftliche Veröffentlichung

Zusammenfassung

The reactivity and selectivity of 1,3-diynes in transition-metal-catalyzed CH activation is exploited to quickly assemble diverse polysubstituted bisheterocycles, which are highly important but difficult to access. By using the CH activation/1,3-diyne strategy, we overcame the challenges of selectivity (chemo-, regio-, and mono-/diannulation) and constructed seven kinds of adjacent bisheterocycles through the formation of four strategic bonds with high efficiency and high selectivity.

Details zur Publikation

StatusVeröffentlicht
Veröffentlichungsjahr2014 (01.07.2014)
Sprache, in der die Publikation verfasst istEnglisch
DOI10.1002/anie.201403782

Autor*innen der Universität Münster

Glorius, Frank
Professur für Organische Chemie (Prof. Glorius)