N-Heterocyclic Carbene-Catalyzed Cascade Reaction Involving the Hydroacylation of Unactivated Alkynes
Biju AT, Wurz NE, Glorius F
Forschungsartikel (Zeitschrift)Zusammenfassung
The N-heterocyclic carbene (NHC)-catalyzed hydroacylation of unactivated alkynes to provide alpha,beta-unsaturated ketones is reported. In addition, a rare case of an efficient and selective dually NHC-catalyzed cascade reaction involving the hydroacylation of alkynes and a subsequent intermolecular Stetter reaction allows the formation of chromanones containing a 1,4-diketone moiety.
Details zur Publikation
Fachzeitschrift: Journal of the American Chemical Society (J. Am. Chem. Soc.)
Jahrgang / Bandnr. / Volume: 132
Ausgabe / Heftnr. / Issue: 17
Seitenbereich: 5970null
Status: Veröffentlicht
Veröffentlichungsjahr: 2010 (05.05.2010)
Sprache, in der die Publikation verfasst ist: Englisch
DOI: 10.1021/ja102130s
Stichwörter: intramolecular stetter reaction activated double-bonds gamma-butyrolactones alpha; beta-unsaturated aldehydes benzoin condensation conjugate umpolung direct annulations efficient enals hydroamination
Autor*innen der Universität Münster
| Akkattu, Biju | |
| Glorius, Frank |