Scanning Probe Microscopy techniques for real time, high resolution imaging and molecular recognition in functional and structural genomics (TIPS4CELLS)

Grunddaten zu diesem Projekt

Art des ProjektesEU-Projekt koordiniert außerhalb der Universität Münster
Laufzeit an der Universität Münster01.02.2005 - 31.07.2008

Beschreibung

High resolution imaging of living cells and subcellular components is essential for functional and structural genomics'. Scanning Probe Microscopy (SPM) has evolved into the imaging method of choice that yields the greatest structural details on biological samples such as proteins, nucleotides, membranes and cells in their native, aqueous environment and at ambient conditions. In addition, due to its high lateral resolution and sensitive force detection capability, the exciting possibility of measuring inter- and intra-molecular forces of bio-molecules on the single molecule level has become possible, leading to new possibilities for the evolution of methods that will enable us to examine the physiological consequences of, even, the interaction of a single ligand molecule with its cognate receptor.In this project we propose to develop Scanning Probe Microscopy to advance the state of the art of this technique. With the support of the Sixth Framework program, Scanning Probe Microscopy is ready to become a mature imaging and measurement platform for cell biology that will become as widespread in the biomedicai laboratory as the confocal microscope, adding value to the European scientific instrument market and giving it a major presence worldwide.

StichwörterScanning Probe Microscopy; SPM; Scanning Force Microscopy
Förderkennzeichen512101
Mittelgeber / Förderformat
  • EU FP 6 - Networks of Excellence (NoE)

Projektleitung der Universität Münster

Oberleithner, Hans
Institut für Physiologie II

Antragsteller*innen der Universität Münster

Oberleithner, Hans
Institut für Physiologie II

Projektbeteiligte Organisationen außerhalb der Universität Münster

  • Scientec (SCIENTEC)Frankreich
  • Jpk Instruments Ag (JPK INSTRUMENTS AG)Deutschland
  • Leiden Probe Microscopy (LPM)Niederlande (Königreich der)
  • Weizmann Institute of ScienceIsrael
  • Johannes Kepler Universität Linz (JKU)Österreich
  • Leiden University (UL)Niederlande (Königreich der)
  • University of Bristol (UNIVBRIS)Vereinigtes Königreich

Koordinierende Organisationen außerhalb der Universität Münster

  • Leiden University (UL)Niederlande (Königreich der)